Cutaneous phaeohyphomycosis caused by Exophiala dermatitidis in an immunosuppressed patient: A case report and brief review

Cutaneous phaeohyphomycosis caused by Exophiala dermatitidis in an immunosuppressed patient: A case report and brief review

Jéssica L. Bueno 1, Iago G. Ferreira 2, Cecília B. Severo 1, Laura Luzzato 3, Melissa O. Xavier 4, Rodrig Vettorato 3

1 Department of Dermatology, Federal University of Health Sciences; Dermatology Service, Santa Casa de Misericórdia; Rio Grande, Brazil; 2 Dermatology Service, Santa Casa de Misericordia de Porto Alegre; Department of Dermatology, Federal University of Health Sciences of Porto Alegre; Porto Alegre, Brazil; 3 Dermatology Service, Santa Casa de Misericórdia, Rio Grande, Brazil; 4 Department of Mycology, Faculty of Medicine, Federal University of Rio Grande. Rio Grande, Brazil

Jéssica L. Bueno, Iago G. Ferreira, Cecília B. Severo, Laura Luzzato, Melissa O. Xavier, Rodrig Vettorato

La información completa de afiliaciones y autor de correspondencia está disponible en la versión original en PDF.

*Correspondence: Cecília B. Severo, Email not available

Abstract

Phaeohyphomycosis is a group of fungal infections caused by filamentous dematiaceous fungi, which have melanin in their cell walls. Phaeohyphomycosis has four clinical forms: superficial, subcutaneous, systemic, and disseminated. Although rare, the subcutaneous form shows a significant prevalence in immunocompromised individuals, especially in solid organ transplant recipients. We report a case of subcutaneous phaeohyphomycosis in a renal transplant patient, caused by the species Exophiala dermatitidis. Although the case reveals characteristic clinical manifestations of the disease, laboratory and cultural findings were atypical. Based on this case of subcutaneous phaeohyphomycosis, a brief literature review is carried out on this rare and important fungal infection in medical practice.

Keywords:  Phaeohyphomycosis. Subcutaneous phaeohyphomycoses. Invasive fungal infections.

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