Erythroderma as first sign of lung cancer

Erythroderma as first sign of lung cancer

Ana G. Lopes 1, Maria J. Guimarães 2, Catarina Cerqueira 3 , Joana Gomes 4, Celeste Brito 3

1 Department of Dermatology,Hospital de Braga, Braga, Portugal; 2 Department of Dermatology and Venereology, Hospital de Braga, Braga, Portugal; 3 Department of Dermatovenereology, Unidade Local de Saúde de Braga, Braga, Portugal; 4 Department of Dermatology, Hospital de Braga, Braga, Portugal

Ana G. Lopes, Maria J. Guimarães, Catarina Cerqueira, Joana Gomes, Celeste Brito

La información completa de afiliaciones y autor de correspondencia está disponible en la versión original en PDF.

*Correspondence: Ana G. Lopes, Email not available

Abstract

Erythroderma, or generalized exfoliative dermatitis, is a rare inflammatory disorder characterized by generalized erythema, involving more than 90% of the body surface area, accompanied by a variable degree of scaling. It may be the clinical presentation of several cutaneous or systemic diseases and it is frequently challenging to find the underlying cause. Our case focuses on a 76-year-old male patient that was referred to our department due to generalized erythroderma and diffuse alopecia, developing over the last 4 months. He presented with erythematous papules and nodules, some of them covered with sticky scales. Skin biopsy was compatible with drug eruption. Due to an inadequate response to treatment and typical B symptoms, further imagiologic studies were performed. Ultimately he was diagnosed with non-small cell lung cancer. This case shows the need to search for a neoplasm in patients presenting with erythroderma, particularly in the presence of systemic symptoms.

Keywords:  Erythroderma. Paraneoplastic dermatitis. Lung cancer.

Contents