Evaluation of dyslipidemia among patients with chronic spontaneous urticaria: a cross-sectional study

Objective: The objectives of this study were to compare the lipid profiles of patients with chronic spontaneous urticaria (CSU) and healthy controls, to identify which lipid parameter is most altered in CSU, and to determine the age and sex group among CSU patients most commonly affected by dyslipidemia. Methods: This cross-sectional study included 30 CSU cases and 30 age-and sex-matched controls. Serum lipids were analyzed through an autoanalyzer; groups were compared using the t-test and X2 test. Results: In our study, dyslipidemia appeared in 53.3% of cases of CSU versus 36.6% of controls. Triglycerides (TG) were significantly elevated in cases compared to controls (p = −0.036), and very low density lipoprotein (VLDL) levels were higher in cases than controls (p = −0.004). The mean age of participants with dyslipidemia was 31.56 ± 7.57 years, with the majority belonging to the 26-35-year age group. Conclusion: This study demonstrates a notable risk of developing dyslipidemia in CSU patients, with TG and VLDL being the most affected parameters.