Nodular hidradenoma mimicking nodular basal cell carcinoma

Nodular hidradenoma mimicking nodular basal cell carcinoma

Elisangela M. A. Lima 1, Mariana O. Fernandes 2, Marina Silva 3, Flávia R. Ferreira 4, Fernanda G. Moya 5

1 Departamento de Medicina, Disciplina de Dermatologia; Serviço de Dermatologia. Hospital Municipal Universitário de Taubaté (HMUT), Taubaté-SP, Brasil; 2 Department of Dermatology, Hospital Municipal Universitário de Taubaté (H.MUT/UNITAU), São Paulo, Brasil.; 3 Department of Dermatology, Hospital Municipal Universitário de Taubaté (H.MUT/UNITAU), São Paulo, Brasil; 4 Dermatology Service, Hospital Municipal Universitário de Taubaté/Universidade de Taubaté (H.MUT/UNITAU) ??? Taubaté-SP, Brazil; 5 Department of Pathological Anatomy, Hospital do Servidor Público Estadual de São Paulo. São Paulo, Brasil

Elisangela M. A. Lima, Mariana O. Fernandes, Marina Silva, Flávia R. Ferreira, Fernanda G. Moya

La información completa de afiliaciones y autor de correspondencia está disponible en la versión original en PDF.

*Correspondence: Elisangela M. A. Lima, Email not available

Abstract

A 40-year-old woman, phototype III, presented with an erythematous, sessile nodule with small ulceration points on the right forearm for 1 year and 6 months. Dermoscopy showed structures similar to blue-gray globules, arboriform telangiectasias with some thickened vessels, bright white spots, and microulceration points. The main hypothesis of nodular basal cell carcinoma (BCC) and excisional biopsy of the lesion were performed. Histopathology showed nodular adnexal epithelial neoplasia without atypia, with a focal connection to the epidermis, a clear cell component, and immunohistochemistry positivity for p63, epithelial membrane antigen (EMA), and cytokeratin AE1/AE3, concluding the diagnosis of nodular hidradenoma. The unusual presentation, mimicking a nodular BCC, and the importance of the correct approach to atypical lesions motivated this report.

Keywords:  Acrospiroma. Basal cell Carcinoma. Dermoscopy. Histology. Immunohistochemistry.

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